MyBioSource.com's STARD6 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, and Western Blot. The STARD6 Antibody (C-term) was generated using STARD6 as the antigen and it reacts with Human.
Description
Cholesterol homeostasis is regulated, at least in part, by
sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM
184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon
sterol depletion, LXRs are inactive and SREBPs are cleaved, after
which they bind promoter SREs and activate genes involved in
cholesterol biosynthesis and uptake. Sterol transport is mediated
by vesicles or by soluble protein carriers, such as steroidogenic
acute regulatory protein (STAR; MIM 600617). STAR is homologous to
a family of proteins containing a 200- to 210-amino acid
STAR-related lipid transfer (START) domain, including STARD6
(Soccio et al., 2002 [PubMed 12011452])